Ultrasonically Activated Irrigation to Remove Calcium Hydroxide from Apical Third of Human Root Canal System: A Systematic Review of In Vitro Studies

I.E. Yaylali, A.D. Keceri, B.U. Kaya

Journal of Endodontics. 2015 Oct;41(10):1589-99.


INTRODUCTION: The aim of this systematic review was to summarize the outcomes of in vitro studies comparing ultrasonically activated irrigation versus other irrigation techniques for removing calcium hydroxide (Ca[OH]2) from the apical third of root canals.

METHODS: The research question was developed according to the PICO strategy. A comprehensive literature search was performed. The Medline, Embase, and TRIP electronic databases were searched. A hand search of the reference lists of identified articles was performed to isolate relevant articles. Two reviewers critically assessed the studies against our inclusion and exclusion criteria. Evaluation of the risk of bias of the studies was performed independently by the 2 reviewers.

RESULTS: After study selection, 62 were assessed for eligibility. Of these, 9 met the inclusion criteria and were included in the systematic review. Because considerable heterogeneity was found in the methodologies, it was not possible to combine the results of studies in a meta-analysis. Ultrasonically activated irrigation was found to be superior to syringe irrigation and apical negative pressure irrigation, but insufficient evidence was found to indicate its superiority over the other irrigation techniques such as sonically activated irrigation, the Self-Adjusting File, (ReDent-Nova, Ra'anana, Israel) and the RinsEndo, (Dürr Dental, Bietigheim, Germany).

CONCLUSIONS: On the basis of available evidence, we determined the effectiveness of ultrasonically activated irrigation compared with syringe and apical negative pressure irrigation. Because of the small sample sizes, low number of included studies, and limitations, further research is needed to confirm our results.


The full article is available online: Researchgate

Yayali review 2015


Additional Info

  • ReDent Nova’s note:

    In this review paper, the authors have not found sufficient evidence to determine whether passive ultrasonic irrigation (PUI) is better than SAF System in removal of Ca(OH)2 or not. However, the two articles that this paper quotes clearly determined that the two techniques achieved similar results, which were superior to other techniques that were examined.

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  • View abstract on PubMed. PMID: 26238527